Numerous scientific papers have been published on OSSEAN®. They report the remarkable performance of this surface compared to others, particularly immediately after implant placement and during the initial phase of healing. The very nature of the healing chain has been reported to be changed and shortened*.
The most critical phase of implant treatment occurs from the moment an implant is surgically placed, through the first weeks of initial healing. It is in this period when most complications and/or adverse effects occur. This juncture also sets the stage for ongoing and long-term future implant success. Naturally, the importance of shortening this time by compressing the healing process is crucial*.
Furthermore, this early accelerated healing process has been documented in “in-vivo” in a bone histological, gene expression, and nanomechanical study. The OSSEAN® surface was shown to play a critical role at the DNA level by favorably enhancing osteoblasts formation and accelerating the mineralization on the newly formed bone*.
Each Intra-Lock® implant is Robotically Micro-Blasted in a clean room environment for precise control. Robotic sequencing and
differential is treatment is utilized to preserve the cutting groove geometry (sharpness) and permit each region of the implant to obtain optimal topography and surface roughness*.
Additional procedures derived from the semiconductor industry and refined for bio-medical applications ensure a clean surface. OSSEAN® Surface is exceptionally free from contaminants as confirmed by XPS-ESCA (Electron Spectroscopy for Chemical Analysis).
-Calcium Phosphate in -Molecular Fusion -Multi-Process Cleaning -Keeps Surface Free from
-Contaminants -Robotic Micro-Blasting Preserves -Cutting Edge Geometry -Cellular Level - Enhanced Osteoblast -Attachment
Molecular Level - -Improved Fibrin -Attachment -Thick Oxide Layer
AFM: Atomic Force Microscopy
OSSEAN® Surface profilometry is well characterized with Atomic Force Microscopy, showing explicit details of its complex surface at various levels of observations*.
This image shows a surface of 20µm x 20µm.
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OSSEAN® Surface structure is engineered to increase host-to-implant biocompatibility and biomechanical response*. It is characterized by having a surface topography that is similar at all levels of magnification, from the surface to the nanoscale level. The repetitive nature of this surface is defined as one that is “fractal” in nature. As with a set of Russian dolls, the structure when viewed at different levels of magnification has the same basic characteristics.
The surface beyond the nanometric level displays an ideal surface for fibrin attachment. At the micrometric level, the pattern is appropriate for platelet deposition*. Under lower magnification, the pattern shows receptor sites that encourage the growth of osteoblasts*.
An electron beam of 15nanometers diameter is shot at various locations on the Ossean® Surface. The edge, bottom and an intermediate location of the surface all show peaks of Ca and P. They are combined in a Calcium Phosphate chemical state as confirmed by the XPS-ESCA.
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When viewed at a maximum SEM resolution (200,000X), OSSEAN® Surface is free of any particles. However, when examined under Auger X-Ray Spectroscopy, calcium phosphate molecules (more than a thousand times smaller than nano particles) are revealed. They are present in the Titanium oxide layer as molecules (Molecular Impregnation), well beyond the nanometric level. These molecules have a greater binding energy than larger particles of calcium phosphate. In addition to extreme stability, the calcium phosphate retains its bioactive properties *.